Ear Center: Hearing Loss

Hearing Loss

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Nurses' Health Study


Hearing loss is the most common disability in the world. It is estimated that of the 28.6 million Americans who are hearing impaired, 18.8 million have moderate-to-severe sensorineural hearing loss (SNHL). The range of hearing loss include: mild, moderate, moderately-severe, severe, and profound.

Recent data from Hoffman et al. have shown that the prevalence of age- and sex-specific hearing impairment in adults 20-69 years continues to decline.

Current hearing loss statistics include:

  • It is estimated that 34.25 million Americans suffer from hearing loss.
  • This rate of hearing loss has doubled from that reported in 1984 (16.2 million hearing impaired).
  • Hearing loss is growing at a rate 60% greater than the rate of growth of the population.
  • 63% of individuals 70 years old or greater have hearing loss.
  • Only 1 in 5 older adults with hearing loss wear hearing aids.
  • 3% of individuals with mild hearing loss wear hearing aids.

Types of Hearing Loss

There are three main types of hearing loss:

  • Sensorineural hearing loss (inner ear, cochlear, or nerve type hearing loss)
  • Conductive hearing loss (ear canal, middle ear, ear bone type hearing loss)
  • Mixed hearing loss (a combination of sensorineural and conductive hearing loss)

Other forms of hearing loss include central auditory processing disorders and auditory neuropathies. Hearing loss may be genetic or occur spontaneously in any particular individual. Hearing loss may be congenital (present at birth), familial, associated with specific syndromes, traumatic, due to infections or tumors, autoimmune, vascular, metabolic, degenerative, or toxic (from medications, chemicals, heavy metals, toxins, etc.)

Evaluation of Hearing Loss

A thorough evaluation of any hearing loss includes a:

  • Complete ear history and physical examination by qualified examiner
  • Hearing testing by a trained audiologist that includes basic audiometric tests: pure tones, bone conduction levels, speech reception thresholds, and word recognitions scores (discrimination). Additional testing may be necessary to diagnose the hearing loss.
  • Sometimes, imaging studies such as CT scans of the temporal bones and/or MRI head scans are indicated.

Treatment of Hearing Loss

Current treatments include:

  • Digital hearing aids
  • Surgical procedures
    • Ear canal and middle ear operations (tympanoplasty, ossiculoplasty, stapedectomy, etc)
    • Middle ear implants
      • Ototronix Maxum hearing implant
      • MED-EL Vibrant SoundBridge hearing implant (not performed at The Ear Center)
      • Envoy Esteem hearing implant
      • Otologic Carina implant (investigational)
    • Cochlear implants
      • Standard cochlear implants (Cochlear Americas, Advanced Bionics, MED-EL)
      • Hybrid cochlear implants (electro-acoustic stimulation)
    • Auditory brainstem implants (ABI not performed at The Ear Center)

Hearing Loss Research

Significant basic science research is on-going concerning the genetics of hearing loss. A promising future technology is "auditory regeneration". Mammalian inner ear cells have been stimulated to differentiate into hearing hair cells in the laboratory. However, the technique has not been performed in any human trials.

A new gene mutation has been identified that may be causing sensorineural hearing loss in children. The gene is called TMTC2. A mutation in TMTC2 may lead to bilateral, symmetric progressive sensorineural hearing loss. In a study with 179 unrelated adults with sensorineural hearing loss, 4% of the patients were positive for a mutation in the TMTC2 gene. TMTC2 testing may lead to early identification of children with hearing loss. See Reference 4 below, Runge et al.

Nurses' Health Study

The Nurses' Health Study II has found that the regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen was linked to a slightly greater risk of hearing loss in young women.

Using data from 55,850 women in the Conservation of Hearing Study (CHEARS), a special sub-study of the Nurses' Health Study, it was found that longer duration of NSAID and acetaminophen use, greater than 6 years for each drug, was associated with a 10% and 9% increased risk respectively. They also found a 7% higher risk of hearing loss among women who used NSAIDs or acetaminophen for 2 or more days per week. In contrast, duration of aspirin use was not associated with an increase in hearing loss. In approximately 5.5% of cases of hearing loss in older women in the NHS cohort, hearing loss may be attributable to chronic NSAID and acetaminophen use. More study is needed.


If you would like to learn more about hearing loss and its treatment, please contact our office at 336-273-9932 and ask to speak to one of our audiologists.


1. Hoffman HJ, Dobie RA, et al. Hearing threshold levels at age 70 years (65-74 years) in the unscreened older adult population of the United States, 1959-1962 and 1999-2006. Ear Hear 2012:33 (May):437-440.

2. Contrera KJ, Betz J, Genther DJ, Lin FR. Research Letter: Association of hearing impairment and mortality in the National Health and Nutrition Examination Survey. JAMA Otolaryngol Head Neck Surg. 2015:141(10);944-946. Click here to download a .pdf copy.

3. Choi JS, Betz J, Lingsheng L, blake CR, Sung YK, Contrera KJ, Lin FR. Association of using hearing aids or cochlear implants with changes in depressive symptoms in older adults. JAMA Otolaryngol Head Neck Surg. 2016;142(7):652-657. Click here to download a .pdf copy.

4. Runge CL, Indap A, Zhou Y, Kent JW, King E, Erbe CB, Cole R, Littrell J, Merath K, James R, Ruschendorf F, Kerschner JE, Marth G, Hubner N, Goring HH, Friedland DR, Kwok WM, Olivier M. Association of TMTC2 with human nonsyndromic sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg. 2016 June 16. doi: 10.101/jamaoto.2016. 1444. (Epub ahead of print).

5. Simpson AN, Simpson KN, Dubno JR. Letters: Higher health care costs in middle-aged US adults with hearing loss. JAMA Otolaryngol Head Neck Surg 2016;142(6):607-608.

6. Hoffman HJ, Dobie RA, Losonczy KG, Themann CL, Flamme GA. Declining prevalence of hearing loss in US adults aged 20-69 year. JAMA Otolaryngol Head Neck Surg 2017;143(3):274-285. Click here to download a .pdf copy.

7. Nurses' Health Study Newsletter, Volume 25, 2017, page 2.


Last revised December 9, 2017